Monday, September 30, 2019

Economic and social conditions Essay

If one is not historical, then it was unscientific. The historical process that had commenced for millennia in the development of societies was a product of scientific processes and vice versa. Friedrich Engels had greatly contributed to the exposition of historical dynamics. A history that was ever changing was always in constant contradiction with the forces within and without. As it had been definitely asserted, historical materialism being a part of a dialectic philosophy was not just narrowly limited to a â€Å"study†. It was a scientific process wherein events were investigated and researched. From these gathered data a hypothesis was derived and tested or compared if that assertion applied to universal condition. History thereof was a result of contradictions, a making of man, not just simply a compilation of events that transpired in the past. Only in such a way that history became a science. Thus Engels, a true revolutionary in his time, presented history according to the material basis of the existence of societies. He discussed the evolution of such societies as subsequent effects of the past that were constantly playing interconnected and interwoven stories. These stories without the other were simply incomplete, hence unscientific. Here he illustrated the formation of history as a result of humanity’s struggle to attain its aims, therefore its own creation and its own being. However, Engels’ history did not consider man simply a being with presupposed actions, knowledge or decisions. To him man was a becoming which had moulded the society that he belongs to. His propensity to survive had been inseparably intertwined with the progress of the economy and to all other aspects of social existence Facts and figures were simply not what history was. Facts and figures did say something but not substantially anything. History was a correlation and interrelationships between and among facts and figures. Without finding those connections, these facts and figures were mere ink and paper –insignificant. Hitherto, Engels’ works remained to be of great influence in the struggles of oppressed peoples and of the international proletariat. This came into reality because Engels’ works were connected to the material foundations of human existence. His ideas and theories were not alienated: theories that were felt and ideas that were tangible and inseparable from the activities of societies. As materialists viewed the nature of humankind and the processes that commenced herein, matter preceded consciousness. Engels’ historical and philosophical analysis did not surface out of mere conception of abstract economic and historical fables. They were a result of the effects of the economic and social conditions existing at that time. Societies came into reality first. From those realities a consciousness was obtained. Engels was enabled to scientifically analyze the future of societies based on the reasons that had caused past societies to progress into what they are at present. Certainly, Engels’ life was no different from the society he intended to explain. What had moulded him in becoming such a great influence in socio-economic paradigms and in the formulation of Marxism surely had a basis in his past. The events that took place during that time were interconnected with his identity. Engels himself was a laboratory of proving that man is a â€Å"becoming† and of contradictions. From these contradictions of the positive and negative factors that had gone through his age, a new form from the antagonisms of the old was drawn. Hence, his life and works were a result of scientific processes. The Friedrich Engels that we knew was a fruit of the reactions among the material conditions that he was exposed to and a synthesis of numerous theses and anti-theses.

Sunday, September 29, 2019

Sniffy Report

The amounts of bar presses for the different training schedules were compared. It was found that non-target behaviors were frequent during the first observation session, but as an association with bar pressing was formed, an increase In target behavior was observed. The IVR schedule produced more target behaviors, and when the reinforce was removed, target behavior decreased. The CRY rat appeared to learn the target behavior more quickly, and the target behavior became extinct more gradually. However, when the reward (virtual pellet) was taken away or decreased, the rats' target behavior decreased.Comparison of CRY and IVR After Shaping 3 Method Participants The sample included fifteen students who shaped virtual rats named â€Å"Sniffs. † These students were In a Psychology 310 class at Clemson University. The class was made up of juniors and seniors In college. Two virtual rats were observed In this experiment using the â€Å"Sniffs† program. These rats were considere d to be representative of the population because they were programmed to behave the way a â€Å"normal,† â€Å"average† rat would. Materials or Apparatus A virtual Skinner Box was used in this procedure. In this box. Ere was a bar for the rat to press and a food dispenser ending at a hopper. Virtual pellets of food were also used In this experiment. Procedure This procedure was conducted In a laboratory setting as an observational study. The experiment consisted of two rats and was between-subject. Observations began with the fifteen students simply observing a virtual rat and recording behaviors that they could possibly study. These behaviors were: sniffing, walking, circling, cleaning, crouching, lying flat, and standing on hind legs. However, the definitions of these behaviors were arbitrary.Three behaviors (bar pressing, rearing, and grooming) were then operationally defined and became the focus of the virtual rats' behaviors. Bar pressing was operationally defined to be when Sniffs pressed the bar that would give him a virtual pellet. Rearing was operationally defined as Sniffs standing on his hind legs against a wall, but not his standing on his hind legs in the middle of the cage. Grooming was operationally defined as Sniffs cleaning his face with his front paws, but not any other type of cleaning behavior. One of the virtual rats Comparison exhibition of these three behaviors was taken from the fifteen students.This was done to define a baseline for â€Å"normal† behavior in these virtual rats. Upon devising this baseline, the students shaped â€Å"Sniffs† for 45 minutes on a continuous reinforcement schedule. The object of training the virtual rat was to teach him how to press the bar and, thus, receive a food pellet. To train him, the students pressed the bar every time Sniffs got close to the food hopper. This caused familiarity with the sound of a bar press, a connection of the sound and the food pellet, and eventually, the connection of the bar press and the food pellet.Thus, Sniffs was trained to press the bar to get food. Because of time constraints, no one in either group completely trained the virtual rats, but for ease of understanding, fully trained rats were used after this part of the procedure. This experiment was done with simulated hungry rats. The students then split up into groups of seven and eight to observe two different virtual rats. The group of seven observed a rat trained on a continuous reinforcement (CRY) schedule, and the group of eight observed a rat trained on a variable ratio-5 (IVR) schedule.The groups observed the virtual rats at different times, but each group observed for 30 minutes. The group observing the rat on a CRY schedule observed and recorded the number of bar presses their Sniffs displayed. The group observing the rat on a IVR schedule recorded the number of bar presses, rearing, and grooming behaviors exhibited by Sniffs. After the virtual rats were trained and observed, the students attempted to extinguish the behavior they trained Sniffs to perform. Both virtual rats were considered to be fully shaped at the beginning of this section of the study.The settings were changed on the Sniffs program so that there was no sound when the bar was pressed. The rats also did not receive any food pellets when they pressed he bar. The rats were observed for ten minutes each at different times. Bar pressing, rearing, Comparison of CRY and IVR After Shaping 5 and grooming behaviors were recorded. Again, because of time constraints, neither rat became completely extinct in the ten minutes of observation, but completely extinct rats were used for the next section of the experiment. Extinction was defined as less than one bar press per minute for the rats.After behaviors for both rats were extinguished, they were placed on their previous schedules of reinforcement to measure recovery behavior. The rats ere observed for twelve minutes in attempt to retr ain them to press the bar for food. Once more, because of time constraints, the virtual rats were set back to full association of bar pressing with food for the remainder of the experiment. Finally, punishment took place. A fully trained CRY virtual rat and a fully trained IVR virtual rat were used in this section. High punishment was implemented for every time the rats pressed the bar.This punishment was a shock from the floor of the Skinner Box. Both rats received this treatment. Each of the rats was observed for five minutes. Bar reusing, rearing, and grooming behaviors were recorded during this time. It is believed that the rat may have thought it was still in extinction, and it is possible that the rat never actually gained the habit back. There were several confound that could have affected the results of this experiment. The lab assistant kept time by incorrect recording of data could have resulted from human error.At times, the virtual rats pressed the bar many times sequent ially, making it difficult to accurately record the data. In this study, the independent variable was the level of reinforcement the rats got when they pressed the bar; these levels were: no enforcement, CRY, IVR, and positive punishment. No reinforcement was used during baseline observations. CRY and IVR were used in training the rats to press the bar and again in recovery. Positive punishment was used in attempt to extinguish the learned behavior of bar pressing in the rats.The dependent variable was the virtual rats' pressing of the bar, Comparison of CRY and IVR After Shaping 6 and data was collected. It is arguable that rearing and grooming behaviors were additional dependent variables, but the one being studied and compared was the bar pressing behavior. There were no ethical problems in this procedure. Virtual rats were used, so no live animals were in danger. These were the only participants in the experiment. The experimenters were also not in danger. The only possible issu e would be stress.The experimenters had a slight amount of stress on them to keep up with the bar presses of these rats. Other than this minor possible dilemma, the experiment was ethically sound. There was no compensation offered in this procedure, and very little bias was likely to play a role in the collection of data. Results Frequency behavior was observed and recorded during this experiment. The IVR rat's training included 118 bar presses for 45 minutes. A noticeable difference was found in the frequency of bar presses for the rat trained on a CRY schedule and the rat trained on a IVR schedule.Figure 1 shows the differences in baseline, CRY, and IVR rat observations of behaviors. Figure 2 gives a comparison of the extinction of the CRY and IVR trained rats. In the twelve minutes the students observed the IVR rat after extinction, no recovery was made. A slight recovery was made in the CRY rat. In the recovery after punishment, the IVR rat pressed the bar four times and did not receive a pellet. The data for all of the observations made can be found in Figure 3. Over all, the differing training techniques appeared to have affects on the response of virtual rats to the independent variable.Comparison of CRY and IVR After Shaping 7 Discussion Hypothesis 1 Hypothesis 1 focused on the observation section of the experiment to define a baseline. It was predicted that more non-target behaviors (rearing and grooming) would occur more often than the target behavior (bar pressing). As seen in Figure 1, the hypothesis was supported. The baseline included almost no bar presses and larger amounts of rearing and grooming. Hypothesis 2 Hypothesis 2 suggested that during shaping, there would be an increase in target behavior and a decrease in non-target behavior as an association was formed.This hypothesis was supported for the rat trained on a IVR schedule, but was not recorded for the rat trained on a CRY. These figures are recorded in Figure 1 . The fact that non-targ et behaviors were not recorded for the CRY rat Hypothesis 3 Hypothesis 3 stated that the rat trained on the IVR schedule would result in more bar presses per minute than the rat trained on the CRY scale. Again, Figure 1 shows this hypothesis to be true. There was a large difference in the amount of bar presses each of the rats exhibited. This is likely because the IVR rats had to press the bar for an unknown number of times in order to receive a food pellet.Comparison of CRY and IVR After Shaping 8 Hypothesis 4 Hypothesis 4 stated that during extinction, the target behavior would increase with the removal of the reinforce. Figure 2 shows this to be true for both rats. When the rats had no motivation to press the bar, they lost interest. There were several extinction bursts, but after the tine often minutes ended, the rats had lost a considerable amount of interest in the target behavior. Implementation This project is applicable to humans in that it demonstrates support for the Beha vioral approach to psychology.A traditional Skinner Box was used, and the traditional ideas of providing reinforcement and punishment as a means of controlling behavior were applied. The ability to compare rat behavior to human behavior is questionable, but a widely- accepted theory was supported in this study. Strengths and Weaknesses This study was done in a small laboratory setting with only two rats. The small number of participants in this study ay be a hindrance in the application of the results to multiple facets. To generalize the study, more rats should be used to test the various shaping methods.Another weakness of this study is that the time measurement was imprecise. The time was kept by the lab assistant, and she occasionally forgot to call the time. Human error plays a part in this as well. Another factor human error likely played a part in is the collection of the data. Although the students were all specifically trying to be accurate in their recordings, it is not li kely that even a single person recorded all of the data refectory. One more weakness includes the fact that the non-target behaviors were not recorded during training of the CRY rat.The data would have been more easily compared if they were consistent across the experiment. Comparison of CRY and IVR After Shaping 9 A major strength in this procedure was the accuracy of averages across the data. Though there were slight differences in the reports of collected data, much of the numbers were close in range. Another strength in this experiment was that the rats being observed were modeled after live rats in a laboratory. Therefore, he experiment was able to be conducted without the use of live animals, and the reported data were likely similar to that from a study on live rats.Further Research This study would be interesting to implement in the lives of humans. Many would argue that rats are different from humans, and therefore, this behavior does not apply to humans. Shaping human beha vior would be difficult to test in a laboratory setting, but if possible, it would be interesting. Parallelism in the observation groups is a good idea to add to further studies. Because this study was missing a few observations, the data collected was less useful to those analyzing it.

Saturday, September 28, 2019

Attention Deficit Disorder Research Paper Example | Topics and Well Written Essays - 500 words

Attention Deficit Disorder - Research Paper Example It is a disorder of hyperactivity and lack of attention as the name indicates. This inattentiveness leads to a cascade of symptoms which makes life very difficult for the patients and they find it difficult to cope with the surroundings (National Institutes of Mental Health 2008; Klass 2010). Attention Deficit Disorder tends to show varying signs and symptoms which may be scaled according to the severity. It tends to affect both boys and girls but the symptoms of increased activity and impulsiveness are seen in boys whereas lack of attention is seen more in girls. Inattentiveness leads to lack of concentration in particular situations as well as inability of focusing capabilities. This also results in lack of the ability to fulfill activities that require attention and focus. The symptoms of increased activeness are restlessness and increased habits of moving around. Impulsiveness is presented in the form of lack of patience and the expression of emotions irrespective of what the oth ers might feel about it (National Institutes of Mental Health 2008; Klass 2010). Radiological studies have highlighted the fact that the frontal lobe of the brain is affected by this disorder and it does not function at an optimal level in the patients suffering from Attention Deficit Disorder.

Friday, September 27, 2019

Marketing the Fashion Product Essay Example | Topics and Well Written Essays - 3000 words

Marketing the Fashion Product - Essay Example The essay "Marketing the Fashion Product" talks about the successful marketing strategy of the biggest clothes retailer in the United Kingdom Marks and Spencer (M&S). The lingerie market has grown steadily over the past decades with the United Kingdom experiencing consistent growth. M&S have grown consistently with new designs, innovative practices to record huge volume of sales in the last 5 years. â€Å"The total UK lingerie market was worth an estimated  £2.93bn in 2010, increasing by 17.8% over the 5-year review period.† M&S underwear brands consist of ‘Autograph’, ‘Per Una’ and ‘M&S Woman’ for women. For men it is ‘Autograph underwear’, ‘collezione’. Marketing has always been the nucleus of any business. There is no other alternative to reach the customers than a proper marketing plan and execution. The companies need to reach out to the customers and offer them the best services and quality at competitive prices. It is not necessary for M&S to provide cheap products as quality is the key to the underwear market segment where comfort counts. The twofold goal of marketing is to attract new customers by promising superior value and to keep and grow current customers by delivering satisfaction. The 7P marketing mix is a scientific account of the key areas of marketing which are Product, Price, place, promotion, packaging, positioning, and people. The idea of marketing mix is the same idea as mixing a cake. A baker will alter the proportions of ingredients in a cake depending on the type of cake he/she wishes to bake. The proportions in marketing mix can be altered in the same way and can differ from product to product.† (GCSE,2001) Product selling is a critical area where the customer habits and trends decide whether they want to purchase the product. Quality and innovative design are key factors where the marketers need to equip themselves with answers to critical questions as to the marketability and the acceptability of a product. Product demand and the trend of the market will decide on the sale of the product. M&S have the uniqueness in them where their innovative designers are constantly researching on the aspect of giving the customer an out of the box design. The body shape wear designed by their experts were special for the customers where they welcomed it and very soon it became the trend setter for the underwear brands. Apart from the core product selling, after sales services are also an important segment of product selling as it gives an element of trust to the company. Price is the second P of the

Thursday, September 26, 2019

Discussion On Non-cargo Claims Case Study Example | Topics and Well Written Essays - 1500 words

Discussion On Non-cargo Claims - Case Study Example Loading and unloading of cargoes in piers must be fast and efficient. Parties who cause the slow pace of the turn-over of those goods do not contribute to the smooth movement of harbor activities and must be penalized. Imposing the sanctions will be an incentive for shippers, consigners, and other parties to make use of port facilities and equipment with the needed efficiency especially within the context of global modernization. Cargo owners are therefore charged with the duty to see the expeditious and orderly loading and unloading of their merchandise and are liable to pay demurrage for any delay in that connection. The payment of such demurrage may not be imposed only in cases of fortuitous or unforeseen events and force majeure or in instances where the guilty party is the carrier which includes its ship captain or master. (Becerra, Robert J. THE DEMURRAGE DILEMMA. December 24, 2007. ShippingDigest. [internet]). In the case at bar, the guilty party is the master of Flying Dustma n and his accountability to compensate for the damage is solidary with the owner of the ship. Horatio has thus nothing to do with the demurrage. It must be importantly noted that the contract between O and Horatio is one of voyage charter where the legal obligations are the burden of the carrier or the shipowner. These accountabilities cover the men and crew of the vessel including the master or the captain. (Compare and contrast the duties, responsibilities, and liabilities of the charterer towards the shipowner under both time and voyage charter parties. LAW ESSAYS UK. the law essay website. [internet]) The execution of the LOF with SCOPIC appurtenant to the Flying Dustman relating to both salvage contractors Pugwash and Saviour does not have any bearing on the possible controversy because the vessel to be salvaged, Flying Dustman, or O, its owner, evidently failed to provide the initial security required by No. 4 of the SCOPIC CLAUSE of SCOPIC 2007 within two working or office da ys from the time that the said SCOPIC CLAUSE was invoked. (SCOPIC CLAUSE. SCOPIC 2007. [internet]) Under this set of facts, Pugwash and Saviour, may opt or choose not to apply the provisions of the said SCOPIC CLAUSE in its totality and may instead go back to the provisions of any subsisting contract in conjunction with Article 14 of the International Convention on Salvage, 1989 (also herein referred to as Convention for brevity) which defines, delineates and enumerates the terms of a special compensation available to salvors or salvage contractors. (Article 14. Special compensation. Chapter III RIGHTS OF SALVORS. International Convention on Salvage, 1989. Admiralty and Maritime Law Guide. International Conventions. [internet]) The rights of the salvors are clearly outlined in the above-cited Convention. At this juncture, it has to be mentioned that the parties are all citizens or subjects of states parties which are likewise members of the International Maritime Organization. The l atter enacted the Convention. The states parties involved are the United States from where the cargoes came and the United Kingdom because of its territory Monserrat where the goods are to be delivered.

Wednesday, September 25, 2019

History of Architecture Essay Example | Topics and Well Written Essays - 1750 words

History of Architecture - Essay Example With an effective symmetry, one-half of the structure is an exact replica of the other half. Such a section is essential in determining the strength and he ability to the entire structure sine it influences the amount of weight that an engineer attaches on either side. The Facade of Pallao Chiericati is one of Palladio’s most prominent work. The symmetry among other pertinent aspects of the structure is similar to those in the early Roman society. He uses the similar rectangular shapes of the structures prevalent in the early society but he further seeks to achieve beauty and durability by modifying the structures and the design of the structures, a new feature in the Roman architecture that is symbolic of his era. Columns on the other hand refer to the solid upright structures that support the entire weight of the building. This is one of the most important aspect of a construction and requires effective consideration in order to reconcile with the total weight of the structu re. In designing his columns, Palladio accentuated his designs with acanthus leaf capitals at the top of the beams. The Roman structures had stronger columns, which just as in any other structure supported the structures. However, he added the design as a means of achieving increased aesthetic features of his design, thereby becoming an important distinction of his works and the new era in architecture that he pioneered. Palladio’s works laid more importance on the symmetry and perspective of the structure. He developed stronger and balanced structures and incorporated more of his creativity on the decoration of the structures thereby making them iconic beauties. He borrowed such aspects of the Roman society thereby earning relevance among them but incorporated his own creativity a feature that marked the transition between the two architectural eras. Among the most common features he used in decorating his works included scallop shells, typical motifs in the Greek and Roman arts. They used pediments to decorate doors and windows (Alain, 2009). Additionally, masks that were important motifs in the early society were used on the interior decoration of buildings. The increased decorations added weight to the building thereby demanding stronger columns and beams to support. Palladio achieved this through the accurate consideration of symmetry and perspective of his work thereby constructing stronger bases capable of withstanding the intense pressure resulting from the heavier walls and roofs. The uniqueness of the design arose from the fact that he used simple and common materials but with them developed stronger and more stable structure, which embodied beauty of the existing cultures (Giovanni, 1980).He designed simple structures, which he developed in bricks and covered in stucco. The stucco walls represented the Roman Villa topology. This way, he upheld the Roman culture in the art of villa constructions. Question 2 The construction technology resulted in stronger structures than those built in modern societies using steel. Basilique Saint-Denis in northern Paris, Canterbury Cathedral and Westminster Abbey in England are some of the early cathedrals whose structures employed the early gothic architecture. Comparing the two to Lincoln Cathedral in England and the Bamberg cathedral

Tuesday, September 24, 2019

Management of change (Reflection) Essay Example | Topics and Well Written Essays - 1000 words

Management of change (Reflection) - Essay Example I was very excited because this gave me an opportunity to have first-hand experience in working in the finance department. The first day was overwhelming since I was still adjusting to my role. I was too scared and did not understand how to go about fixing problems. In the course of the simulation, I was able to identify an area that I excelled in the process of managing change. I could identify areas that need change. For example, previously writing on invoices manual on paper. I was able to identify this shortcoming and introduce E-invoicing. That was a change that was welcome since no one wants to use paper. Management of change is all about timing. In the event that I noticed a shortcoming, I was quick to respond. The decision-making in the event of a need for change is an area that I noticed that I was good in ensuring effective management of change. Helping other employees in the process and adapting to change was another area I was effective in. I could take up helping other employees that met difficulties in the change process, which is necessary to ensure that the company moved forward as a whole. Accepting the possibility of making mistakes is also necessary for the change process. I noticed my lack of composure in the event of any change as a shortcoming. The new responsibilities bestowed upon me overwhelmed me. I reacted by avoiding the problem presented in the event of change. I found myself running away from the problems on the first day . I avoided tasks that needed a lot of concentration This was a sign of weakness and resistance to change. Being good at decision-making and deciding when and how to change things in the wake of a change was an area I was good. This is in the case of introduction of E-invoicing Problem-solving ability in managing change in the event that the invoice clearing was not on time and offering a solution was a strong point. I was also good at accepting challenges.

Monday, September 23, 2019

CIS Questions Coursework Example | Topics and Well Written Essays - 1000 words

CIS Questions - Coursework Example Determine if they can be used simultaneously in a page. If so, explain which of the two takes precedence over the other. Javascript is utilized for one line and customization where CSS is utilized in multiple webpages to ensure that aesthetics of a page are consistent. Javascript is utilized more for web page validation and action whereas CSS is used for style and design. 12. Imagine that you designed a Website for a client using JavaScript to make animated snowflakes fall on the page. When you test the page, the animations do not work. Predict what the problem could be and propose a solution. 13. Analyze some of the limitations a Web designer should be aware of before adding JavaScript to a Website. Determine if these limitations outweigh the benefits of using JavaScript. Explain your decision. From the server or client side, the processing power can be a huge factor. Additionally, web pages with many scripts. It can take a long process to execute because of the algorithm that it must process. 14. From the second e-Activity, identify a company (bank, car wash, travel agency, nonprofit, restaurant, etc.). Keeping that company in mind, select the client-side or server-side scripting you would most likely use, and why. Or you can explain the client-side or server-side scripting you would not use, and why not. I used to take this course as a Business Analysis and specialized in e-marketing which allowed me to harness my growth in this realm. My future position will IT director in BA. The demand for Business Administration undoubtedly has boomed over the recent years along with marketing. It is one of the best scope in the commerce market for various reasons First and foremost, the specialization of marketing in BA is a perfect fit in e-commerce. I will be exposed to many realms of technology that exploits many channels of the business. In the modern century, internet marketing has become one

Sunday, September 22, 2019

The Functionalism of Gangs in New Zealand Essay Example for Free

The Functionalism of Gangs in New Zealand Essay Gangs have been perceived as a predominant and rising social issue in New Zealand since as early as the 1950s. Associations of crime and deviance have been the focus of media and law enforcement throughout this time but the issues associated with gangs do not prevail singularly within the construct of the groups. It is too easy to point the finger to those on the fringes of society and say that they are the cause for social instability. It is harder to look at those ‘issues’ that seem to impede society and say that they actually have a function that keeps society stable. This essay will seek to underline the key influences of gang life in New Zealand and its effect on society from a functionalist perspective, employing Erik Durkheim’s theories, New Zealand sociologist expertise and other affiliated sources. The purpose is to explore the functions of gangs within the context of society as a whole to prove that they indeed have positive attributes that keep communities and society healthy. The three main areas this essay will be targeting are cultural breakdowns, economic instability and ‘unity and purpose’. The rise of gangs in New Zealand began as early as the 1920s but there was no systematic study of them until the 1950s (Gilbert, J. , 2013). The struggle for identity is one of the main causes for the increase in gang memberships during the New Zealand urbanisation that many Maori experienced in the 1960s. They suffered enormously from a break in traditional forms of their cultural structure as they migrated to the cities for work. The problem that arose from the exodus from rural to urban living was the breakdown of their cultural identity and traditional forms of power and hierarchy (Gilbert, J. . Cited by Turner (1973) in the European Journal for Social Psychology; ‘an insecure social identity for members of a low-status group would follow when they have some awareness that their inferiority is not completely inherent, fixed or legitimate’ (p304). This suggests that Maori who were part of the urbanization saw and noticed the change to their social status and took action to change their social inferiority. It was here gangs became an effective tool within society to deal with the large numbers of individuals that were not coping within a functional system. Ill-equipped to deal with the many realities of city living, and with the breakdown of traditional forms of authority, young Maori faced with ‘multiple marginality’ formed gangs in unprecedented numbers. † (Gilbert, J. , p292). Gangs here have proven not only to become effective surrogate communities for those who have suffered from cultural breakdowns but also have actively provided a rise of status for individuals who had become marginalized. It is this function, creating identity and community, that gang membership has proven to be a staple for maintaining healthy individual lives. Emile Durkheim’s most famous work is his study of suicide which recorded and proved statistics of suicide in relation to crisis such as economic instability and people who experienced ‘anomie’ (lack of social regulation) or ‘egoism’ (lack of social integration) (Cree, p 10). His argument was that intensely personal decisions, such as suicide, were actually influenced by the functions of the community and society people are part of. If the functions and stability of those environments then breakdown, statistics recorded by Durkheim have shown that there is an increase in depression and suicide. A functionalist perspective would then argue that the provision of gangs recreated stability for many Maori during the urbanization period, and not only in ways of community and hierarchy. Gangs were also a provision for economic stability. â€Å"The faltering economy of the 1980s reshaped gang membership. With few employment options to entice members toward conventional lifestyles the gangs became not just vehicles of rebellion but a means to achieve social and material fulfilment. † (Gilbert, p 292) Economically gangs provided security through many forms of work, both legal and illegal. Even now substances like marijuana are an important economic aspect of communities facing decline in isolated and rural areas of New Zealand, such as the East Coast and Northland (Giddens, p 239). Although the work gangs provided was often illegal it was (and still is now) an essential component for those who were struggling during economic upheaval. If anything, even in modern New Zealand, the system of the gang actually controls and manages the illegal behaviour of the individuals within it, as they have to conform to the power structures and hierarchy. The structures of power within gangs were not only good for consolidating members into their communities but also for providing unity amongst its members through having a shared purpose. Through this unity they have evolved into more sophisticated entities and are commonly known as a significant part of certain communities (Gilbert, p286). The reason that this is so is because many gang members share common identities with the communities they are embedded in, on economic grounds as well as cultural grounds. In these communities gangs often provided security and a focal point for decisions and issues that surround the people. This security can be critical for specific communities, the majority of which face marginalization because of ethnicity or economic status. Emile Durkheim suggested in his 1895 work that ‘law and morality’ were the key components for individual happiness. â€Å"Durkheim thus insists that human happiness is realised, not through the satisfaction of individual wants and needs, but through the creation of social harmony,† (Cree, p 10). It is here we see and can begin to accept the importance of the unity of the gang. A functionalist at this point would argue that it is by the existence of entities such as gangs, who create social acceptance for those marginalized, that quells higher statistics of suicide within New Zealand. The gangs provide unity, hierarchy, purpose and social standing; all of the things Emile Durkheim believed were essential for individual happiness and a prosperous society. This essay has covered several different aspects of gang evolution within New Zealand which have significant and positive attributes that contribute to a functioning society. In this regards I would argue that gangs are not an issue that needs a solution within New Zealand, nor would society benefit from their eradication. In saying this this essay did not cover many of the negative aspects of gangs, including gang violence and rivalry. In its defence this essay would conclude, there is no social structure – whether schools, businesses, families or churches – that do not have negative attributes, but that does not impede them in terms of their function within a healthy society. Gangs within New Zealand society play a larger role for social stability than people realise. Society within New Zealand does not have adequate coping tools to deal with people who have been marginalized or faced with extreme identity crisis due to cultural shifts within their life. Gangs have proven with their structures of hierarchy, provision of security and accessibility within lower socio-economic communities that they have an important function within society and play an essential role in maintaining the social health of those drawn to their communities.

Saturday, September 21, 2019

Organizational Behavior-Communication Essay Example for Free

Organizational Behavior-Communication Essay 1. Present which channels of communications should be emphasized and how these channels will be used to ensure that the traditional departments (e.g., IT, human resources, customer service, and sales) at SWC headquarters have necessary accurate and timely information. Communication in an organization or company is very important in achieving goals and objectives. It is oftentimes used in relaying information, messages and issues that concern the success of a company or organization. It is the medium used by most of the high ranking officials and members to have an organized and timely delivery of information in every office or department for instance. Various types of communication or channels had been used. These communication channels are used by the companies to convey and interact well with the employees in order to improve and attain growth of the organization. There are two types of channels—indirect and direct communication. Indirect communication is used when the interaction is not face-to-face. It uses medium such as different types of technologies like computers, monitors and among others. The most common type of indirect communication is the teleconferencing.   On the other hand, direct communication is a face-to-face type of communication. This is common when all of the members of the team are present in just one area. 2. Which channels will be key to those work teams with all members located within headquarters? In the case of SWC, all of the members of the team are within the headquarters, it is best to use direct communication. In relaying this message , a memo can be sent to the members of the team to inform them of the activity that will be done within the headquarters. It is a common knowledge that doing a meeting or gathering within a certain place when all of the people are present, it is best to employ the direct communication. If the head of the department do not have the time to write a memo the most common thing done is to send an email to the members stating the information and issues that should be discussed and later on meet face-to-face with the members. It is not advisable that the leader will just send an email to all the members even if all are present within one area. On the other hand, an email might be good to relay the information fast and easy but still it connotes something to the members. The members might think that the leader of the team is not interested in talking with them. So, there are also strengths and weaknesses of these channels. But in this case, a good leader nurtures a relationship with the members through constant socialization, constant talking with them and assuring that the company is still wants them and will be like a friend that whenever the company decides to change leadership and people the members will be the first to know. It is showing of sincerity with the members of the team. In a study done by the Harvard business school, they projected what a good manager is. They found out that the effective manager spends more than 80 percent of their time in interacting with their personnel and staff. Furthermore, their study said that interaction and conversations within the working area is important in leading a company or organization. It is human capital and social capital that is working in order to achieve and create what the company wants such as increasing productivity while enhancing innovation. In another research done by Ron Burt from the University of Chicago, a leading researcher on the social capital of managers has found, through numerous studies, that certain patterns of connections that individuals build with others brings them higher pay, earlier promotions, greater influence, better ideas and overall greater career success. Burt believes that good social capital provides a much higher return on investment in human capital the two work together. (K rebs, 2005) In another research done at the Norwegian school of economics, a manager or team leader with a better social networking were more productive since they are sincere with their work, they can easily coordinate with the members without hesitation and coordinate tasks in order to finish a certain project and accomplish the goals and objectives of the project (Krebs, 2005). 3. We may have virtual self-managed teams with members located in different parts of the world. The members have yet to meet each other. These teams are each focusing on designing and delivering specific products to certain customers by designated dates. On the other hand, while face-to-face interaction is important in achieving productivity the introduction of various technologies cannot be ignored. Some of the teams of SWC are located in various areas where there is difficulty of meeting face-to-face. In this kind of interaction, teleconferencing has been used by many organizations and companies in order to hold a meeting or to discuss an issue that concerns the company. Also, one of the successful interactions is through networking. This technology helps individuals communicate with each other even if it is across the world. It is a laborious and costly though but once it is set up many of the staff outside the headquarters will benefit from it. From this networking there will be better information flow and exchange of communication among the team members(Lussier, 2005) If SWC were to consider the virtual self-managed teams, below are some key areas that would be evaluated. A virtual self-managed team has been around the globe today. It is used by the outsourcing companies such as call centers, medical transcriptionist, and even tutorials online. Through the introduction of the technology people have embraced this and been nurturing and disseminating it to the others. But before going into a deeper context of the virtual self-managed team, a creation of this team is very important such as choosing the right person to manage and disseminate information. There are a lot of criteria in choosing the person. One of this is the knowledge and skills on the technology that will be used in the entire implementation of the project or program. Individuals who are adept with various types of technologies and willing to be trained again and again just to ensure that there will be no problems later on in the implementation.   Individuals who have lots of connections and networks that can assist them with their problems in terms of technology. Individuals who are willing to share later on their knowledge and not be tacit about the new information and studies so that there will be transfer of skills., and someone that cannot only design programs but can facilitate information flow and sharing of knowledge. a. What communication channel(s) would you recommend for the initial meeting? For the initial meeting of the team, it would be best that is done face-to-face. This is the first meeting so it should build rapport with each other. Even if there are the use of technologies later on, at least during the initial meeting and introduction of each other there already a communication among them. b. What communication channel(s) would you recommend as key interactions (you are not limited to those channels listed in the exhibit)? Later on, after the initial meeting the team can discuss issues through teleconferencing, phone calls, chat messengers and among others that might not require the presence of each other and spend costly fares just to be in one place. Organization of the issues beforehand is also important because this will identify how urgent the meeting should be or is it just one of the meetings and phone calls would be enough. c. Explain how these teams will meet the challenges of each of the stages of group/team development. Engaging in this kind of set-up, virtual self-managed team, is difficult to maintain though. It will require energy because this does not only entail communication but it also needs feedback and learning (source) among the team members. In order to meet these challenges there should be a constant communication even it is called â€Å"virtual† because through this monitoring can be done as well as learning along the way. d. What challenges does diversity present? What must be done to meet these challenges? Diversity in people is very challenging. Every person has its own personality, culture and attitude. Constant learning through trainings can be a good answer to it. e. From a communications point of view, what are the advantages and what are the disadvantages of virtual self-managed-teams? Virtual self-managed team is cost-effective. The only costs that will be incurred are the gadgets that will be used during the networking and conferencing. It can also be done anywhere and anytime of the day. Just put the set up and voila there will be a meeting in the middle of beach. On the other hand, it has also disadvantages. Since it will not require the presence of the person it does not nurture a relationship and does not build rapport among the team. Oftentimes than not, the reaction and the feelings will be not be felt if it is only in the monitor or phone calls. Conversations can be faked and might build walls.

Friday, September 20, 2019

Nursing Processes for Emesis Management

Nursing Processes for Emesis Management Nausea and vomiting are common complications of multiple conditions, procedures, therapies, and events such as motion sickness, pregnancy, anesthesia (general, regional, or local) or radio/chemotherapy. Symptoms can be debilitating for many patients, and in the case of post-operative nausea and vomiting (PONV) physical damage may result, such as rupture of sutures, stitches, and esophageal tissue, and metabolic problems, such as electrolyte imbalances and dehydration (Golembiewski et al, 2005; Gan 2006). In severe cases of PONV, although rare, aspiration of gastric contents may occur, resulting in pulmonary sequelae, such as pneumonia or pneumothorax (Scuderi and Conlay 2003; Bremner and Kumar 1993). Thus effective treatment of PONV, possibly through multimodal antiemetic prophylaxis, is an important are of research (Skledar et al. 2007). This essay will consider two commonly used, well-recognized antiemetic treatments namely cyclizine and prochlorperazine. Both represent very old drug therapies, with cyclizine having been launched as an antiemetic in 1953, and prochlorperazine as an antipsychotic in 1957 (Broccatelli, 2010), its use as an effective antiemetic emerging soon thereafter (Finn et al, 2005). These drugs are commonly used on most wards in my practice setting and therefore it is vital for nursing staff to understand their respective pharmacodynamic (PD) and pharmacokinetic (PK) profiles. Prior to prescribing it is also important that the nurse have relevant knowledge regarding how these drugs work, how their PD and PK properties are altered by disease processes such as kidney/liver failure and whether there are any relevant contraindications or precautions. Additionally, the potential for drug-drug interactions and the dose appropriate for the patients age and weight should be ascertained if beneficial pati ent orientated outcomes are to be achieved. These issues will be comprehensively discussed within this essay. Pharmacology of emesis There are a plethora of drugs on the market to treat emesis, however, deciding upon an appropriate and effective treatment for patients requires the cause of the underlying nausea and vomiting to be ascertained. This is because the symptoms can manifest as a result of a number of underlying pharmacological processes, as will now be described. Vomiting is a complex reflex action controlled by the vomiting centre (VC) in the medulla region of the brain, an important part of which is the chemotrigger zone (CTZ); stimulation of this in turn leads to VC stimulation which ultimately leads to vomiting (Goodman Gilman, 1996). Neurotransmitter mediated stimulation of the VC can arise from both peripheral and central impulses (Shanbhag, 2008). Thus gastrointestinal irritation, motion sickness and vestibular neuritis all manifest in nausea and vomiting as a result of neurotransmitter release. The three main neurotransmitters involved in the control of vomiting are acetylcholine (ACh; via muscarinic-receptors), dopamine (via dopaminergic receptors), histamine (via H-1 receptors), and serotonin (via 5-HT3 receptors) (Shanbhag, 2008). Inhibition or antagonism of these receptors achieves emetic control. The VC has neurons which are rich in muscarinic cholinergic and histamine containing synapses and is directly stimulated by the vestibular input (e.g. through motion sickness), whilst dopamine and serotonin release are involved in the visceral stimuli pathway (e.g. through chemotherapy treatment) and also in the CTZ stimulation pathway as shown in Figure 1. Thus drug classifications of anti-emetics arise on the basis of which of the three pathways that they target (Flake et al., 2004). Selective serotonin receptor antagonists and antidopaminergics target the visceral stimuli and the CTZ, whilst the antihistamines and anticholinergics target the vestibular input pathway (Hornby , 2001; Flake et al., 2004). Etiology of Nausea and Vomiting Cyclizines anti-emetic effects are not fully understood but it is thought that it works by blocking the transmission of information from the labyrinthine apparatus in the inner ear (i.e. the vestibular pathway) to the VC (Goodman and Gillman, 1996). Cyclizine may also target the CTZ and it thought to exhibit some ACh muscarinic receptor blockade which probably contribute to the antiemetic potential thus operating at several pathophysiological levels. However, a side effect of ACh blockade is sedation in some individuals along with the potential for certain deliriant and hallucinogenic effects, probably responsible for cyclizines abuse potential (Bailey and Davies, 2008). Cyclizine produces its antiemetic effect within two hours and it lasts approximately four hours (emc, n.d.). The exact mechanism of prochlorperazines antiemetic action is also unclear, but the drug is thought to inhibit apomorphine induced vomiting by blocking dopamine D2 receptors centrally in the CTZ and possibly peripherally through dopaminergic receptors in the intestine (Perwitasari, 2011).   However, it also has some potential to block anticholinergic and alpha-adrenergic receptors, and therefore can also result in sedation along with muscle relaxation, and orthostatic hypotension (Kelly, 2000). Following intramuscular administration prochlorperazine has an onset of action within ten to twenty minutes and a duration of action of three to four hours (globalrph, n.d.). Indications and dosage form Cyclizine is indicated for the control of postoperative and drug-induced vomiting and in motion sickness (BNF, 2012; emc, n.d.). It is given by mouth at a dose of 50mg tablets up to three times a day or parenterally as a 50mg in 1ml solution intramuscular (im) or intravenous (iv) injection again at a frequency of up to 3 times a day (Reynolds, 1993). The recommended dose in children aged 6-12 years is lower: 25 mg up to 3 times daily. For motion sickness, it is recommended that tablets be taken 1-2 hours before departure. Cyclizine can also be given for vertigo and, morning sickness in pregnancy, and to combat  opioid nausea. It is also prescribed for radiation sickness (medsafe, n.d.) and PONV (Cholwill et al., 1999), indeed it is given iv before the induction of general anaesthesia at half the recommended dose, to increase the lower oesophageal sphincter tone thus reducing the hazard of regurgitation and aspiration of gastric contents (medsafe, n.d.). Although prochlorperazine is classified as an antipsychotic, its principal use nowadays is in the treatment of severe nausea and vomiting of various causes including, PONV, vertigo and motion sickness (BNF, 2012). It has several dosage forms: tablet (5mg: one or two tablets 3-4 times daily), syrup (5mg in 5ml: 5-10 ml 3-4 times daily), suppositories (25mg twice daily), dissolvable tablet (buccal tablet 3mg: one or two tablets twice a day in adults and children aged 12 years and over), im injection (12.5mg in 1ml; 5-10mg repeated every 3-4 hours with a maximum daily dose of 40mg) and iv injection (2.5 -10 mg by slow IV injection or infusion  with a maximum daily dose of 40mg). The oral (and buccal) route is the only method of administration recommended for children, and it is not recommended in children younger than  12 years (BNF, 2012). The different dosage form of prochlorperazine provides the nurse with flexibility for example the elderly and children may prefer the syrup or b uccal tablet, or in dysphagia suppositories or intra-muscular injections could be more appropriate. Cyclizine and prochlorperazine are both considered first line treatments for nausea secondary to vertigo and motion sickness (Quigley, 2001) and are first line treatments in many hospitals in PONV (NHS, Salisbury; NHS Plymouth). A review by Matchar, et al. (2003) has suggested that oral prochloperazine may also be used as an adjunct in the treatment of nausea associated with migraine (Matchar et al, n.d.). No randomized controlled trial has been found which formally compares efficacy of cyclizine and prochlorperazine, however, two studies comparing cyclizine with perphenazine in ameliorating drug-induced emesis, have shown the former to have comparable antiemetic efficacy to this related phenothiazine drug (Dundee et al., 1975; Chestnutt and Dundee, 1986). These studies are featured in a Cochrane report (Stevenson, 2006) which investigates drugs for preventing PONV and highlights eight drugs which reduce PONV by a similar amount in this patient group, cyclizine being one. The report concluded, therefore, that the most important question to answer when treating emesis is What are the types and risks of side effects experienced by patients exposed to these antiemetics? Thus safe and effective prescribing requires the nurse to identify patient variables or comorbidities relevant to the drugs side effects, for example heart failure patients should not be prescribed cyclizine and individuals susceptible to visual disturbances should avoid prochlorperazine as per the drugs contraindications. It is noteworthy that both drugs may be prescribed in the later stages of pregnancy if considered appropriate by a doctor (Schaefer, 2007; CKS, n.d.).  [1]   The choice of antiemetic would depend upon the precise cause of the nausea in conjunction with the specific receptor affected. However, since several different neurotransmitters stimulate the CTZ, combining drugs with different mechanisms of action can often be more effective than increasing the dose of one individual drug (King and Brucker 2011). Indeed, combinations of antiemetics are often used in palliative care (NHS Scotland, n.d.). Notably, vomiting of unclear or mixed origin may respond to a phenothiazine such as prochlorperazine because, in addition to acting on dopamine and serotonin receptors in the CTZ, it also acts at the VC and vestibular area. Cyclizine and prochlorperazine are both commonly used anti-emetics in palliative care where nausea and vomiting are present in up to 70% of patients with advanced cancer (NHS Scotland, n.d.). Treating this patient population requires particular vigilance, since there may be a number of underlying reasons for and comorbidities contributing to the nausea and vomiting, and antiemetics may be inappropriate. Consideration for causes of the symptoms might include intestinal obstruction or constipation, anxiety, raised intracranial pressure (ICP), oesophageal candida, severe pain or hypercalcaemia all of which might warrant interventions other then antiemetics. Conversely, should the nausea and vomiting be identified as drug induced, then anti-emetics such as cyclyzine or prochlorperazine might be appropriate. Raised intracranial pressure stimulates vomiting centre via pressure receptors and can be problematic in patients with known or suspected brain metastases. Notable, cyclizine can be g iven to such patients, especially where corticosteroids are contraindicated (NHS Scotland, n.d.). Pharmacokinetics Cyclizine, like most antihistamines, is well absorbed from the GI tract. After oral doing the effects develop within 30 minutes, are maximal within 1-2 hours and lasts for 4-6 hours. A single oral dose of 50 mg cyclizine in healthy adult volunteers resulted in a peak plasma concentration of approximately 70 ng/mL, occurring at about two hours after drug administration. The plasma elimination half-life is approximately 20 hours.  [2]  Cyclizine is extensively metabolised in the liver via N-demethylation to the inactive metabolite norcyclizine (Figure 4), which is widely distributed throughout the tissues and has plasma half-life of approximately 20 hours. This metabolite has minor antihistaminic activity compared to parent drug. A single 50 mg dose of cyclizine when given to an adult male volunteer, results in less than 1% of the total dose administered being excreted as parent drug in the urine over a 24 h period. Thus urinary excretion of metabolite rather than parent drug is th e major route of elimination for  cyclizine. The metabolism is thought to be mediated through CYP 2D6 and therefore exhibit inter-subject variability dependent upon the CYP 2D6 genotype as demonstrated by Vella-Brincat et al. (2012) in their study of the PK of cyclizine (Appendix 1) and its major metabolite (Appendix 2) in palliative care patients receiving sub-cutaneous cyclizine. Results indicated that the metabolic ratio of parent drug to metabolite differed significantly according to CYP2D6 genetics.  [3]   Prochlorperazine is reasonably well absorbed from the GI tract and highly protein bound. It undergoes extensive metabolism both in the gastric mucosa and on first pass through the liver via the cytochrome P450 enzyme system (CYP 2D6 and CYP 3A4)  [4]  to inactive metabolites, which are subsequently excreted in the urine. Parent drug has a plasma half-life of between 4 and 8 hours, the precise half-life differing according to the mode of administration. An im injection produces its antiemetic effect in 5-10 minutes and it lasts for 3-4 hours. Onset of effects are related to the mode of administration hence the pharmacokinetic profile, thus an oral dose would have a slightly slower onset of action but would last longer compared with an im injection.  [5]  According to Finn et al (2005), although the drug has been accepted as a useful anti-emetic for over half a century, its therapeutic success has been limited by its low and variable absorption and high first-pass metabolism. H owever, the development of a new buccal formulation has improved the PK, since studies demonstrate that buccal administration of prochlorperazine produces plasma concentrations more than twice as high as an oral tablet, with less than half the variability (Finn et al., 2005)  [6]  (Figure 5). When placed in the buccal cavity between the upper lip and the gum the formulation forms a gel from which the prochlorperazine is released and absorbed. The plasma levels achieved at steady-state on a dosage regimen of one 3mg buccal tablet twice daily are similar to those observed with the standard oral dosage of one 5 mg tablet taken three times daily. The elimination half-life of prochlorperazine in this formulation is 9 hours. The safety and efficacy of this relatively new formulation has also been demonstrated by Bond  [7]  (1998) in a randomised, double-blind, double-dummy trial in patients with vestibular disorders. Side effects By virtue of their pharmacology, cyclizine and prochlorperazine are both central depressants and can cause impairment of performance (Benson, 2001). Consequently, the pharmaceutical data sheets for both drugs have warnings regarding their potential to interfere with the ability to drive or operate machinery safely due to their ability to cause drowsiness (BNF, 2012). Despite the fact that cyclizine is one of the older antihistamines it is considered less potent in this regard compared to others in its class (Broccatelli, 2010), however, there is considerable variability in response to this side effect which can range from slight drowsiness to deep sleep. For this reason in practice, when one drug is not effective or poorly tolerated then it is justifiable to give another drug or combination of drugs (Benson, 2001). This unwanted side-effect is also a feature of prochlorperazine especially in the elderly, and often diminishes with continued treatment of both drugs (emc, n.d.). Cyclizines other more common side-effects include headache and psychomotor impairment plus antimuscarinic effects, such as urinary retention, dry mouth, blurred vision, and gastrointestinal disturbances (BNF, 2012). Less common side effects are palpitations and arrhythmias, also dizziness, hypotension, muscular weakness and poor coordination (Goodman and Gilman, 1975). Prochlorperazine commonly causes CNS related side effect such as acute dystonia or dyskinesia, however these tend to be transitory (usually occur within the first 4  days of treatment) and are more common in children and young adults. Dopamine antagonists like prochlorperazine can also cause extrapyramidal effects, QT prolongation and even severe hypotension, especially in the elderly (emc, n.d.). Muscle spasms and restlessness are other reported side effects. Interactions Cyclizine exhibits pharmacological interactions with other drugs due to antagonism of its action (donepezil, galantamine, rivastigmine) or enhanced anticholinergic actions (tacrine, trimethobenzamine, triprolidine, trospium). Pharmacokinetic interactions may arise since cyclizine is an inhibitor of the hepatic CYP 2C9 isozyme system, which is involved in an NADPH-dependent electron transport pathway. This isozyme oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics and contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan. Pethidine and propanidid are also listed as having a potential to interact with cyclizine. Cyclizine also acts as an inhibitor of estrogen sulfotransferase, the enzyme responsible for estradiol metabolism. Prochloperazine has a plethora of interactions, both pharmacological and pharmacokinetic. The pharmacokinetic interactions are largely due to competitive metabolic interactions at the hepatic CYP 3A4 and CYP 2D6 enzymes. The CYP 3A4 isozymes are responsible for a variety of oxidation reactions e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1-hydroxylation and midazolam 4- hydroxylation, plus metabolism of structurally unrelated compounds, including steroids, fatty acids, and many other xenobiotics. Whilst the CYP 2D6 isozymes are responsible for the metabolism of many drugs and environmental chemicals, via oxidative transformation along with metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.  [9]  Consequently, the data sheet for prochlorperazine lists many drugs with interaction potential including adrenaline, amphetamine, carbamazepine, clonidine, desferrioxamine, guanethidine, levodopa, lithium, phenobarbital and propranolol. Managing Drug Therapy When managing the care of a patient, nursing staff must initially thoroughly assess the patient, then identify significant interactions between core drug knowledge (PD, PK, ADRs, interactions, contraindications) and the patients core variables (health status, age and gender, life-style and diet, environments, culture). Thereafter the nurse can plan and implement suitable interventions, which will maximise therapeutic effects whilst minimising adverse effects (Aschenbrenner and Venable, 2008). In order to achieve such objectives the nurse should ensure administration of the appropriate medication is given through a suitable route on a regular basis or as required, with ongoing patient evaluation and monitoring. Cyclizine and prochlorperazine are both considered first line treatments for nausea secondary to vertigo and motion sickness (Quigley, 2001) and are first line treatments in many hospitals in PONV (NHS, Salisbury; NHS Plymouth). A review by Matchar, et al. (2003) has suggested that oral prochloperazine may also be used as an adjunct in the treatment of nausea associated with migraine (Matchar et al, n.d.). No randomized controlled trial has been found which formally compares efficacy of cyclizine and prochlorperazine, however, two studies comparing cyclizine with perphenazine in ameliorating drug-induced emesis, have shown the former to have comparable antiemetic efficacy to this related phenothiazine drug (Dundee et al., 1975; Chestnutt and Dundee, 1986). These studies are featured in a Cochrane report (Stevenson, 2006) which investigates drugs for preventing PONV and highlights eight drugs which reduce PONV by a similar amount in this patient group, cyclizine being one. The report concluded, therefore, that the most important question to answer when treating emesis is What are the types and risks of side effects experienced by patients exposed to these antiemetics? Thus safe and effective prescribing requires the nurse to identify patient variables or comorbidities relevant to the drugs side effects, for example heart failure patients should not be prescribed cyclizine and individuals susceptible to visual disturbances should avoid prochlorperazine as per the drugs contraindications. It is noteworthy that both drugs may be prescribed in the later stages of pregnancy if considered appropriate by a doctor (Schaefer, 2007; CKS, n.d.).  [10]   The choice of antiemetic would depend upon the precise cause of the nausea in conjunction with the specific receptor affected. However, since several different neurotransmitters stimulate the CTZ, combining drugs with different mechanisms of action can often be more effective than increasing the dose of one individual drug (King and Brucker 2011). Indeed, combinations of antiemetics are often used in palliative care (NHS Scotland, n.d.). Notably, vomiting of unclear or mixed origin may respond to a phenothiazine such as prochlorperazine because, in addition to acting on dopamine and serotonin receptors in the CTZ, it also acts at the VC and vestibular area. Cyclizine and prochlorperazine are both commonly used anti-emetics in palliative care where nausea and vomiting are present in up to 70% of patients with advanced cancer (NHS Scotland, n.d.). Treating this patient population requires particular vigilance, since there may be a number of underlying reasons for and comorbidities contributing to the nausea and vomiting, and antiemetics may be inappropriate. Consideration for causes of the symptoms might include intestinal obstruction or constipation, anxiety, raised intracranial pressure (ICP), oesophageal candida, severe pain or hypercalcaemia all of which might warrant interventions other then antiemetics. Conversely, should the nausea and vomiting be identified as drug induced, then anti-emetics such as cyclyzine or prochlorperazine might be appropriate. Raised intracranial pressure stimulates vomiting centre via pressure receptors and can be problematic in patients with known or suspected brain metastases. Notable, cyclizine can be g iven to such patients, especially where corticosteroids are contraindicated (NHS Scotland, n.d.). Administration Precautions Due to its centrally acting effects, patients taking cyclizine should avoid alcohol and other depressants e.g. hypnotics or tranquillisers. Food may reduce irritation to cyclizine and since there is no interaction with food, this drug can be taken without regard to meals. The datasheet indicates it should be used with caution in hepatic disease, whilst in renal impairment there is a need for dose reduction (BNF, 2012). Cyclizine should also be used with caution in patients with severe heart failure. Other anticholinergic effects include visual disturbances, and sedation, which can make them dangerous for the elderly population or younger patients. Further, cardiovascular side effects e.g. hypotension, tachycardia, and palpitations have been reported, plus minor GI effect e.g. dry mouth and constipation. Cyclizine has a well-known abuse potential (Ruben et al. 2006). In opiate dependents receiving long-term methadone cyclizine is often taken in large doses intravenously to provide a m ore intense high. Thereafter the addict experiences depressive mood changes and a craving for cyclizine. Many individuals receiving long-term prescriptions of oral methadone have been identified as being habitual abusers of cyclizine.  [11]  Consequently, there is considerable reticence by pharmacists in prescribing the drug, and alternative treatments are generally sought. Obviously in the hospital setting there is little opportunity for such abuse, and the efficacy and cost-effectiveness of the drug would therefore take precedence over its abuse potential (Barber, 1995; Philips and Thompson, 1997). Although prochlorperazine being an antipsychotic phenothiazine drug can be employed in psychiatry, in lower doses it is usually prescribed for its anti-emetic properties. Patients taking the drug should take with a full glass of water, avoid excessive quantities of coffee or tea (containing caffeine) and also avoid alcohol. Prochlorperazine should be used with caution in patients with renal and hepatic impairment and cardiovascular disease; also in Parkinsons disease, epilepsy and in patients with a history of glaucoma. While the drug does not deliver the euphoria that is associated with many commonly abused drugs, it still has some abuse potential since it can alter mood and perception, but not to the extent of cyclizine. Moreover, dependence and tolerance can develop, which can drive the individual to continue to seek more of the drug  [12]  and result in overdose, characterised by symptoms of central nervous system depression to the point of somnolence or coma. Agitation and r estlessness may also occur in overdose. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus. Managing Drug Therapy Nausea and Vertigo: In emetic patients, antiemetics should only be prescribed when the underlying cause is known, indeed antiemetic administration may be harmful when the cause can be treated, e.g. in diabetic ketoacidosis or digoxin/antiepileptic overdose. In addition to motion sickness cyclizine can be given to patients with nausea caused by mechanical bowel obstruction and raised intracranial pressure.  [13]  Once a decision has been made that antiemetic drug treatment is appropriate, the drug and the dosage form should be chosen according to the aetiology of vomiting along with core drug knowledge and patient variables. Thus prochloperazine is useful for episodes of more severe nausea and vomiting e.g. associated with diffuse neoplastic disease, radiation sickness, and the emesis caused by drugs such as opioids, general anaesthetics, and cytotoxics. Indeed, prophylactic use may be required if severe nausea is anticipated such as following chemotherapy treatment. (Aschenbrenne r and Venable, 2008). Prochorperazine may be a suitable choice because of its dosage forms, thus rectal suppositories can be useful in patients with persistent vomiting or with severe nausea and the buccal tablet dosage form is also useful in such instances. However, during use of phenothiazines it is important to monitor severe dystonic reactions, especially in children. It is recommended as a second-line treatment for vomiting in pregnancy after promethazine.  [14]   Whereas the efficacy of cyclizine in treating nausea and vomiting has already been unequivocally proven, it is only available in tablet and injectable form. Nevertheless, cyclizine may be the choice of drug over prochlorperazine in children since in this patient population the latter can only be administered orally (BNF, 2012), and therefore requires patient compliance for success. There is no evidence that either of the two drugs is superior to the other in terms of efficacy; also despite cyclizines longer plasma half-life compared with prochlorperazine, the duration of action is similar at around 4 hours. The adverse event profiles do however differ slightly, because of the differing underlying pharmacology of these two drugs. This is an important consideration in the choice of drug, alongside special precautions which, as described earlier, must be considered in conjunction with patients co-morbidities. It is also noteworthy that educating patients and their families regarding the drug of choice is important; for example warning patients against consuming alcohol with both prochlorperazine and cyclizine and warning patients against driving or operating machinery if susceptible to drowsiness with either drug. In summary, both cyclizine and prochloperazine have similar safety, tolerability and toxicity profiles despite their differing modes of action on a cellular level. Tolerability in terms of drowsiness is a potential problem for both drugs, but is generally dependent upon the individual patients susceptibility, warranting a trial and error type approach when determining which is the optimal drug of choice. Also, due to the drugs both being substrates of CYP 2D6 their phamacokinetic profiles may exhibit inter-subject variability by virtue of the different phenotypes of this enzyme which exist in the population. This differing pharmacokinetic profile would logically translate into a varied response in terms of therapeutic effects. Likewise, their potential to interact with other drugs is inextricably linked with their metabolism, namely metabolic competition at the cytochrome P450 enzyme receptor sites. Thus both drugs have the potential to interact with a wide range of other medications . Moreover, since both drugs are extensively metabolised in the liver, with excretion of metabolites in the urine, there is a need for caution in renal and hepatic disease. Cyclizine and prochlorperazine appear to be similarly efficacious with regard to their treatment of emesis caused by motion sickness. The literature is inconclusive regarding which drug would be more superior for PONV, or vertigo, and even though it has been suggested that prochlorperazine should be chosen over cyclizine when the nausea is severe, there does not seem to be any compelling evidence for this and many hospitals tend to choose cyclizine over prochlorperazine in their antiemetic protocols/guidelines. The most compelling evidence for choosing prochlorperazine over cyclizine in the primary care setting would be the high abuse potential with cyclizine. However, in the secondary care setting this is of minimal concern. Therefore a more compelling reason for choosing prochlorperazine over cyclizine in this setting might largely hinge on the greater flexibility in formulations available for prochlorperazine. Whereas both drugs can be given orally as a tablet, when patients are vomiting this may be inappropriate. The buccal tablet or rectal suppository, which is available for prochlorperazine, and is less invasive than an injection formulation may be more acceptable to many patients in such cases. To conclude, the present essay has demonstrated that the nursing process for effectively dealing with emesis is challenging and complex. Here we have witnessed the plethora of facts which the nurse must take into account prior to prescribing the antiemetic drugs cyclizine and prochlorperazine, and that even after attempting to optimise drug selection on the basis of such facts, success cannot be guaranteed. Ongoing monitoring of patient response/progress with the possibility of altering or augmenting the chosen drug therapy is necessary to improve outcomes, ensure patients receive optimal care, and that they enjoy maximal therapeutic success with minimal side effects. References Matchar DB, Young WB, Rosenberg JH, Michael P. Pietrzak, Stephen D. Silberstein, Richard B. Lipton and Nabih M. Ramadan. Evidence-based guidelines for migraine headache in the primary care setting: Pharmacological management of acute attacks. Available at: www.aan.com/public/practiceguidelines/03.pdf/. Accessed 28/10/12. CKS: Clinical Knowledge Summaries http://www.cks.nhs.uk/nausea_vomiting_in_pregnancy/management/prescribing_information/prochlorperazine/advice_about_prochlorperazine Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 607). Benson A J, Medication for Motion S

Thursday, September 19, 2019

Overcoming the Constraints of Society Essay -- literary Analysis, Kate

he focus of this paper will be to examine Kate Chopin’s The Awakening chapter ten, specifically paragraphs five to ten. Throughout The Awakening Edna is constantly fighting with the expectations of society and her desire to be a free woman. As a woman, Edna is expected to be the perfect wife and mother, however she longs to embrace and free her creative self. Because of this battle within herself she shows many of the characteristics of depression. The passage mentioned above is very symbolic of Edna’s fight to overcome her mental illness. The thesis of this paper is that Edna’s yearning to swim is a metaphor for her longing to overcome depression, patriarchal expectations and societal constraints. By taking an in-depth look into the author’s word choice, a parallel can be found between learning to swim and the ability to overcome the depression within. The water mentioned in the passage is symbolic of Edna’s depression, and the fact that she had been trying to learn how to swim shows that she is trying to conquer it. Edna’s inability to swim shows that she was struggling to defeat her depression, however she was actively trying to find help by asking others for assistance. Edna describes that â€Å"A certain ungovernable dread hung about her when in the water† (Chopin 73), this shows her fear of succumbing to the depression but also her anxiety to rise above it. By giving in to the depression Edna would accept society’s expectation of her, she would have to become the perfect mother and wife at any cost. Meanwhile, in order for her to rise out of the depression she would have to give in to her desire to be free of these expectations. Before Edna was able to swim, she describes herself as a â€Å"tottering, stumbling, clutching chi... ... the water in this passage, and her decision on whether or not to conform to the expectations of society. Her inability to swim in the beginning exhibits how Edna has been conforming to the expectations of society by becoming both a wife and mother, and as a result has developed the depression. Edna was able to defeat her depression, represented by her learning how to swim, by choosing the more solitary path. It can also be seen that Edna’s hold on her depression is very unsteady and wavering, which shows that she might not be able to control it. In the end she was â€Å"reaching out for the unlimited in which to lose herself.†(Chopin 74), which shows that she is unable to contain her creative self within and she is looking for an escape from society. It also represents that she cannot keep control of her depression and that she is also looking for an escape from life.

Wednesday, September 18, 2019

Rice Works to Keep Gaza Pullout on Track :: essays research papers

Rice Works to Keep Gaza Pullout on Track By BARRY SCHWEID, AP Diplomatic Writer 1 hour, 8 minutes ago WASHINGTON - Secretary of State Condoleezza Rice scrambled her schedule Friday to add a trip to the Middle East designed to nurture Israel's promised withdrawal from Gaza and part of the West Bank despite a spate of terror attacks. ADVERTISEMENT With the pullout a month away, State Department spokesman Sean McCormack said, "All the parties need to make the maximum effort to see that this disengagement process is a success." McCormack gave no precise date for Rice to meet with Israeli and Palestinian leaders, but the trip was tacked onto one to Africa she is expected to undertake next week. "It's a potentially historic moment, and the parties should seize the opportunity to realize all the potential from this disengagement," the spokesman said, indicating Rice also wants to look beyond this summer's Israeli pullback. McCormack said Rice would cover Senegal, Sudan, Israel and the Palestinian territories from Tuesday through July 24. In spite of a surge of terror attacks, Israeli Prime Minister Ariel Sharon remains committed to pulling all settlers and troops out of Gaza and part of the West Bank. But Sharon has frequently made clear that he does not intend to give ground under threat of terror. Rice's diversion to the region from Africa, where she had been considering a number of stops, was announced after a flare-up of violence that threatened an already tattered Mideast truce. Rice has used telephone diplomacy in the last few days to try to keep Israel and the Palestinians on track to an orderly withdrawal and to encourage Palestinian leaders to go after terrorists. She told Palestinian leader Mahmoud Abbas, while returning on her jet plane from an Asian trip Wednesday, that he must take immediate action to find and prosecute those responsible for the killing of four Israelis this week in Netanya.

Tuesday, September 17, 2019

Human resource management activities in healthcare Essay

There are many external and internal factors that might affect the health care organizations; however they are more likely to be affected by external forces that in turn affect their daily operations. Some of the factors that affect the human resource department of a healthcare organization are mentioned below. †¢ Economic factors †¢ Social and cultural changes †¢ Technological changes †¢ Legal changes HR planning and analysis Premeditated planning is a procedure that allows the health care associations to direct their future actions utilizing the resources that are accessible to them while keeping in mind the goals of the organization. There are some internal and external strength that have to be taken care of by the association and then a SWOT Analysis should be carried out. Some of the advantages of Human Resource planning are that it permits effectual use of workers and assists to replace the significant vacancies that have to be filled. Furthermore, planning suggests realistic recruitment projections, facilitates the staffing resources to be utilized more proficiently and efficiently and it also allows a improved focused investment in training and retraining, growth, career counseling and efficiency enrichment and also assists to uphold as well as to get better the level of variety. Human Resource planning is a very fundamental part of premeditated planning in addition to strategic HR planning, it assists to examine and classify the need for and accessibility of HR so that the association can meet its goals. Pynes, 2004). Projections aids in appraising the current condition and to estimate future demand and affairs by looking at the history trends of the association and is significant for the associations in a way that it assists to predict the retirement plans of the staff whereas the demand estimate helps to foresee the labor force that would be required in the future. EEO compliance EEO stands for equal employment opportunity and this expression was shaped by President Lyndon B.  Johnson when he marked Executive Order 11246 on September 24, 1965, formed to forbid federal contractors from discerning against workers on the grounds of race, sex, creed, belief, color, or nationality. Recently most managers have also added sexual compass reading to the directory of non-discrimination. The Executive Order as well required contractors to put into practice affirmative achievement plans to augment the contribution of minorities and females in the place of work. Pursuant to federal policy, affirmative achievement plans must comprise of an equivalent opportunity plan statement, an examination of the existing work force, recognition of problem areas, the establishment of objectives and schedules for mounting employment prospects, definite action-oriented plans to tackle problem areas, support for society action plans and the establishment of an internal audit and reporting structure. (EEOC, n. d. ). The reason why employment opportunity equal is important is because it is morally a right way to conduct oneself in the workplace, moreover it also helps in making the business prosper. The way that I move toward civil rights laws and employment civil rights laws, is I in fact think that they are all connected, they are all civil rights laws, anti-discrimination laws in the place of work, whether anti-discrimination on the grounds of race, sex, disability, age, creed or nationality they are all entrenched in the similar bedrock standard and i. e. , that individuals should be judged in the place of work, based upon their capability to carry out the job and not based upon the threats, myths and typecast that one may have because of their race, or gender, or disability, or age, belief or nationality. That is in fact the unifying feature of all of the regulations in which the EEOC puts into practice and imposes, I think that is really significant that is both rising out of my own personal understanding and what I feel is right; that people should be judged based upon their ability to do the job†¦ and that’s really the very simple core of what we do. And if you sort of take that notion, that principle, one step further, or take it one step, it makes business better. To the extent that you’re making employment decisions in the workplace, whether they be on the basis of hiring somebody for a job or promoting somebody for a job, or treating somebody on the job, you ground those workplace decisions in the ability of that individual to do the job, rather than on a stereotype, or a fear, or a myth, because that person is from a different race than you, or a different religion, or looks different, or is older, or doesn’t walk, or moves around or communicates in a different way from you. If you base those workplace decisions, upon the ability of that individual to do the job, you will get the most qualified person. You won’t let internal biases, or fears, or myths, or stereotypes get in the way of selecting the best qualified person. Therefore I think, it is in best interest of the business to strip away those typecasts, those threats and those myths, in order to obtain the best competent person, because then company will really be improved. The Quotations page, n. d. ). Other considerations Some of the other considerations the human resource management in the health care organizations has to take care of are staffing, development of employees, compensation, health, safety and employee and maintaining labor management relation. Staffing The HR department must ensure that a fair selection policy is being used when hiring a candidate and everyone should be given an equal opportunity. Moreover, the job should be made available for every person who has the potential to do it and for this both internal and external recruitment should be opted for. Other than this, it is also essential to provide clear job criteria for the vacancies that are being announced by the human resource department of a healthcare organization. Full supervision must be done to ensure that the right candidate has been hired after which training should be provided to him. (Shi, 2006). Development of employees Health care organizations should invest in training to augment individual performance and organizational productivity, moreover it should also focus on developing management skills/development and supervisory skills, technical skills and communication skills and provide training to the employees who are new in the organization especially the ones who are working or are hired for lower-level positions in order to augment their performance. Compensation This comprises the wages and bonuses, vacation payment, sick leave payments, recompense of the staff and insurance policies, etc. , it is HR Department that is in command to expand and to direct the benefits compensation structure for the workers that serve as an incentive to promise the staffing. Their objective does not just come to an end after staffing but they also have to work on retaining workers and make them stay on with the organization. Once the employee is hired, it is the duty of the benefits coordinator to explain the benefits and the incentives the employee can expect from the organization so that the employee is aware about it in the beginning and he does not get discouraged later onwards. Health and safety It is essential for the organization to ensure safety of employees at the workplace and the health care organizations must their employees’ health and medical benefits and the employees should be given free medical services. Employee management relation and Labor management relation It is essential for the HRM at the healthcare organization to avoid any kind of discrimination in context with the age, gender, race or religion of an employee and it is basically the duty of the HR department to take care of this so that fair treatment is given to each and every person. Moreover, the HR department must also provide the assistance of negotiation in case any issues arise between the employees working at any level in the organization in order to ensure a healthy work environment. In the same way, the HR department also has to manage the labor and have good terms with them as well. (Leat, 2001).

Monday, September 16, 2019

Neutrality of money

The â€Å"neutrality of money† refers to the notion that the effect of changes in an economy’s nominal supply of money will have no effects on the real variables like the real GDP, employment and consumption and only the nominal variables such as the prices, wages and the exchange rate are affected. It was the standard feature of the classical[1] macroeconomic model of unemployment and inflation that was based upon the assumption of quickly clearing perfectly competitive markets and the money market was governed by the quantity theory (Ackley, 1978). This resulted in what was known as the â€Å"classical dichotomy† – the real and monetary sectors of the economy could be analysed separately as real variables like output, employment and real interest rates would not be affected by whatever was going on in the nominal segment of the economy and vice-versa. The objective of the present endeavour is to explore this concept of neutrality by delving into its theoretical motivations and basis and thereby introspecting upon the extent to which distinguishing between short run and long run neutrality are important before briefly exploring the possible methods of empirically investigating the notion and concluding. In the standard classical macroeconomic model, which was the basis of answering all macroeconomic questions before Keynes’s General theory brought forth its capturing   assault onto it, the connection between the money supply and the price level was made through the quantity theory thus implying that the price level would vary to ensure the real aggregate demand, which was assumed to be a function of the real money supply, was in alignment with the available supply of output determined in the market for labour. The quantity theory simply posits that real money balances are demanded in proportion to real income. This can be expressed as MD/ P = (1/v).Y; where MD represents the nominal demand for money balances, P the price level, v the velocity of circulation of money and finally Y the real GDP.   Now by assumption, v is constant; MD equals the supply of money which is exogenous (MD, = MS = M) in equilibrium and Y is fixed at its equilibrium value (Y= Y*) determined in the labour market. As a result the quantity theory equation essentially becomes an equation that determines the price level for different levels of money. We have,  Ã‚  Ã‚   P = v.(M/Y*) . Evidently, changes in the money supply now shall only influence the prices. This is the basis of the notion of neutrality of money which therefore is a direct derivative of the assumption of the quantity theory itself (Carlin and Soskice, 1990). An increase in the supply of money initially leads to a rise in the aggregate demand above the real output (Y*, which is exogenous to the money market) due to increased availability of cash balances. Due to the excess demand situation the prices are pushed up until the demand for real output reduces to equal the supply of it. Note that in the classical system, the rate of interest plays the role of equating savings and investment at full employment and does not enter the money market. However, in the 1930s the great depression which was essentially a situation of cascading mass unemployment had no convincing explanation in terms of the classical framework which proposed that an economy would always operate at full employment. This situation of mass unemployment and the lack of forthcoming explanations of the phenomenon in terms of the classical full-employment framework provided the context for the introduction of the Keynesian model of unemployment. Although he upheld the assumption of perfectly competitive markets, he assumed prices to be fixed and money wages to be rigid and inflexible especially in the downward direction in the short run thereby implying the inability of the prices and wages to adjust to excess supply situations in the labour market; employment and output were determined by the effective aggregate demand in the product market. Consumption was assumed to be a function of real income implying savings, essentially the remainder of real income after consumption to be a function of real income as well rather than a function of real rate of interest as in the classical framework, and aggregate demand was made up of the planned expenses for consumption, investment and government expenses (for a closed economy). Contrary to the classical model, in the Keynesian framework the rate of interest serves in equating real demand and supply of money rather than equating investment and full employment savings. This set up not only brings forth the possibility of equilibrium with unemployment prevalent in the labour market, it also dispels the concept of neutrality of money. An exogenous increase in the money supply through its effect on the real rate of interest affects the amount of investment and through that causes a change in the aggregate demand and thus in the real output and employment. So, this framework proves the non-neutrality of money the short run (Mankiw, 2000). But in the long run, money can be deemed to have neutral effects through the following reasoning. An increase in the money supply will reduce the interest rates and increase investment. However, as the money supply rises, the real stock of money balances exceeds the desired level thus necessitating the expenditure on goods to be raised in order to re-establish the optimum and in that creating an excess demand in the goods market. In the long run prices and wages are perfectly flexible and in the presence of excess demand, there is a rise in the price level until the excess demand is satisfied, at the new equilibrium. Again this rise in prices leads to an increase in the demand for money and thus leads to a restoration of the real interest rates and investments to their initial levels (Patinkin, 1987). Therefore, in the long run money supply increases have no effects on real interest rates, investment, or output in the long run. So, we find that although money is actually non-neutral in the long run due to the wage-price inflexibility in the short run, in the long run money has neutral effects. Infact, Patinkin (1956) notes that not only is money neutral in the short run but this short run neutrality is absolutely necessary for the quantity theory to hold. If this non-neutrality is denied and the classical dichotomy is accepted, then there is no theory of money, quantity theory or otherwise. Testing the neutrality of money would require one to measure the effects of altered money supply has on real variables like the real GDP, employment and real interest rate. One approach possible would be to use a time series data set with values for these variables. A regression would be run to ascertain the extent of effects if any, the changes in money supply over time has had on the real variables. In fact, Fisher and Seater (1993) have used time series data in this manner to test the neutrality of money. Their methodology however requires the usage of advanced econometric tools. Many consequent studies[2] have adopted this methodology to test time series data for different regions and check for neutrality of money. Another option would be to use cross section data with different regions specified by different money supply values. By gauging the differences in the values of the real variables of these regions and relating these with the differences in the money supply values through regression analysis can be another way of testing for neutrality of money. So, to sum up, we have seen that although short run neutrality of money is not a valid proposition, money does not have real effects in the long run. In the final section we have suggested two possible approaches to testing the neutrality of money. References: Ackley, G., (1978). Macroeconomics: Theory and Policy, New York: Macmillan Boschen, J.F. & Otrok, C.M., (1994) Long run neutrality and superneutrality in an ARIMA framework: comment, American Economic Review 84, 1470-1473. Carlin, W., & Soskice, D., (1990) Macroeconomics and the Wage Bargain: A Modern Approach to Employment, Inflation, and the Exchange Rate, U.K.: Oxford University Press Fisher, M.E. & Seater, J.J., (1993) Long run neutrality and superneutrality in an ARIMA framework, American Economic Review 83, 402-415. Mankiw,   N.G., (2000) â€Å"macroeconomics† 4th ed, Worth publishers, New York Patinkin., D. (1987) â€Å"Neutrality of money,† The New Palgrave: A Dictionary of Economics, v. 3, pp. 639-4 Patinkin, D., (1956) Money, interest and prices: An integration of monetary and value theory, New York: Row Peterson [1] One should be beware of the misleading potential of the term classical and note its distinct presence in macroeconomics and its modern adoptions in the forms of new classical economics and thereby avoid confusing it with the school of economic thought associated with Marx, Smith and Ricardo. [2]   e.g., Boschen and Otrok (1994) for the US